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Exosome-guided bone targeted delivery of Antagomir-188 as an anabolic therapy for bone loss
The differentiation shift from osteogenesis to adipogenesis of bone marrow mesenchymal stem cells (BMSCs) characterizes many pathological bone loss conditions. Stromal cell-derived factor-1 (SDF1) is highly enriched in the bone marrow for C-X-C motif chemokine receptor 4 (CXCR4)-positive hematopoiet...
Autores principales: | Hu, Yan, Li, Xiaoqun, Zhang, Qin, Gu, Zhengrong, Luo, Ying, Guo, Jiawei, Wang, Xiuhui, Jing, Yingying, Chen, Xiao, Su, Jiacan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917458/ https://www.ncbi.nlm.nih.gov/pubmed/33718671 http://dx.doi.org/10.1016/j.bioactmat.2021.02.014 |
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