CRISPR/Cas9 Mediated Knock Down of δ-ENaC Blunted the TNF-Induced Activation of ENaC in A549 Cells

Tumor necrosis factor (TNF) is known to activate the epithelial Na(+) channel (ENaC) in A549 cells. A549 cells are widely used model for ENaC research. The role of δ-ENaC subunit in TNF-induced activation has not been studied. In this study we hypothesized that δ-ENaC plays a major role in TNF-induc...

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Detalles Bibliográficos
Autores principales: Shabbir, Waheed, Topcagic, Nermina, Aufy, Mohammed, Oz, Murat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917654/
https://www.ncbi.nlm.nih.gov/pubmed/33673381
http://dx.doi.org/10.3390/ijms22041858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917654/
https://www.ncbi.nlm.nih.gov/pubmed/33673381
http://dx.doi.org/10.3390/ijms22041858

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