Testicular Germ Cell Tumors Acquire Cisplatin Resistance by Rebalancing the Usage of DNA Repair Pathways

SIMPLE SUMMARY: Germ cell tumors are a model of curable solid tumors due to their unique sensitivity to cisplatin-based chemotherapy. Patients are typically young adults, and despite high cure rate, about 20% of them do not achieve remission or relapse, and 50% of them succumb to the disease. The me...

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Detalles Bibliográficos
Autores principales: Caggiano, Cinzia, Cavallo, Francesca, Giannattasio, Teresa, Cappelletti, Gioia, Rossi, Pellegrino, Grimaldi, Paola, Feldman, Darren R., Jasin, Maria, Barchi, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917736/
https://www.ncbi.nlm.nih.gov/pubmed/33668653
http://dx.doi.org/10.3390/cancers13040787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917736/
https://www.ncbi.nlm.nih.gov/pubmed/33668653
http://dx.doi.org/10.3390/cancers13040787

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