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Testicular Germ Cell Tumors Acquire Cisplatin Resistance by Rebalancing the Usage of DNA Repair Pathways
SIMPLE SUMMARY: Germ cell tumors are a model of curable solid tumors due to their unique sensitivity to cisplatin-based chemotherapy. Patients are typically young adults, and despite high cure rate, about 20% of them do not achieve remission or relapse, and 50% of them succumb to the disease. The me...
Autores principales: | Caggiano, Cinzia, Cavallo, Francesca, Giannattasio, Teresa, Cappelletti, Gioia, Rossi, Pellegrino, Grimaldi, Paola, Feldman, Darren R., Jasin, Maria, Barchi, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917736/ https://www.ncbi.nlm.nih.gov/pubmed/33668653 http://dx.doi.org/10.3390/cancers13040787 |
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