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A Single Point Mutation, Asn(16)→Lys, Dictates the Temperature-Sensitivity of the Reovirus tsG453 Mutant
Studies of conditionally lethal mutants can help delineate the structure-function relationships of biomolecules. Temperature-sensitive (ts) mammalian reovirus (MRV) mutants were isolated and characterized many years ago. Two of the most well-defined MRV ts mutants are tsC447, which contains mutation...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917769/ https://www.ncbi.nlm.nih.gov/pubmed/33673179 http://dx.doi.org/10.3390/v13020289 |