Elevated Trehalose Levels in C. elegans daf-2 Mutants Increase Stress Resistance, Not Lifespan

The C. elegans insulin/IGF-1 (insulin-like growth factor 1) signaling mutant daf-2 recapitulates the dauer metabolic signature—a shift towards lipid and carbohydrate accumulation—which may be linked to its longevity and stress resistance phenotypes. Trehalose, a disaccharide of glucose, is highly up...

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Detalles Bibliográficos
Autores principales: Rasulova, Madina, Zečić, Aleksandra, Monje Moreno, Jose Manuel, Vandemeulebroucke, Lieselot, Dhondt, Ineke, Braeckman, Bart P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917784/
https://www.ncbi.nlm.nih.gov/pubmed/33673074
http://dx.doi.org/10.3390/metabo11020105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917784/
https://www.ncbi.nlm.nih.gov/pubmed/33673074
http://dx.doi.org/10.3390/metabo11020105

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