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Plasticity of Treg and imbalance of Treg/Th17 cells in patients with systemic sclerosis modified by FK506

To determine the effects of Tacrolimus (FK506) on Treg cells and subpopulations in SSc patients and assess the ability of FK506 to modify the immune imbalance of Treg/Th17 cells. We analyzed PBMC from five SSc patients and six healthy control by flow cytometry after cultured with 0, 0.1, 1, or 10 ng...

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Detalles Bibliográficos
Autores principales: Liu, Xinjuan, Wu, Yu, Li, Mengtao, Hao, Jianyu, Wang, Qian, Zeng, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917869/
https://www.ncbi.nlm.nih.gov/pubmed/33631989
http://dx.doi.org/10.1177/2058738421998086