CRISPR Deletion of a SVA Retrotransposon Demonstrates Function as a cis-Regulatory Element at the TRPV1/TRPV3 Intergenic Region

SINE-VNTR-Alu (SVA) retrotransposons are a subclass of transposable elements (TEs) that exist only in primate genomes. TE insertions can be co-opted as cis-regulatory elements (CREs); however, the regulatory potential of SVAs has predominantly been demonstrated using bioinformatic approaches and rep...

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Detalles Bibliográficos
Autores principales: Price, Emma, Gianfrancesco, Olympia, Harrison, Patrick T., Frank, Bernhard, Bubb, Vivien J., Quinn, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917899/
https://www.ncbi.nlm.nih.gov/pubmed/33671852
http://dx.doi.org/10.3390/ijms22041911

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917899/
https://www.ncbi.nlm.nih.gov/pubmed/33671852
http://dx.doi.org/10.3390/ijms22041911

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