Unlocking the Secrets of Cancer Stem Cells with γ-Secretase Inhibitors: A Novel Anticancer Strategy

The dysregulation of Notch signaling is associated with a wide variety of different human cancers. Notch signaling activation mostly relies on the activity of the γ-secretase enzyme that cleaves the Notch receptors and releases the active intracellular domain. It is well-documented that γ-secretase...

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Detalles Bibliográficos
Autores principales: Ghanbari-Movahed, Maryam, Ghanbari-Movahed, Zahra, Momtaz, Saeideh, Kilpatrick, Kaitlyn L., Farzaei, Mohammad Hosein, Bishayee, Anupam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917912/
https://www.ncbi.nlm.nih.gov/pubmed/33673088
http://dx.doi.org/10.3390/molecules26040972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917912/
https://www.ncbi.nlm.nih.gov/pubmed/33673088
http://dx.doi.org/10.3390/molecules26040972

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