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Analysis of the Conditions That Affect the Selective Processing of Endogenous Notch1 by ADAM10 and ADAM17

Notch signaling is critical for controlling a variety of cell fate decisions during metazoan development and homeostasis. This unique, highly conserved signaling pathway relies on cell-to-cell contact, which triggers the proteolytic release of the cytoplasmic domain of the membrane-anchored transcri...

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Detalles Bibliográficos
Autores principales: Alabi, Rolake O., Lora, Jose, Celen, Arda B., Maretzky, Thorsten, Blobel, Carl P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918056/
https://www.ncbi.nlm.nih.gov/pubmed/33673337
http://dx.doi.org/10.3390/ijms22041846