MicroRNA-497-5p downregulation inhibits cell viability, reduces extracellular matrix deposition and induces apoptosis in human hyperplastic scar fibroblasts by regulating Smad7

Hypertrophic scars (HSs) are characterized by excessive extracellular matrix deposition and excessive growth of dense fibrous tissues. MicroRNAs (miRNAs/miRs) serve key roles in HS formation. The present study investigated the expression, role and mechanism underlying the effects of miR-497-5p in HS...

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Detalles Bibliográficos
Autores principales: Li, Zhiqiang, Wang, Pengtao, Zhang, Jie, Zhao, Dongkui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918061/
https://www.ncbi.nlm.nih.gov/pubmed/33680106
http://dx.doi.org/10.3892/etm.2021.9815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918061/
https://www.ncbi.nlm.nih.gov/pubmed/33680106
http://dx.doi.org/10.3892/etm.2021.9815

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