A SNaPshot Assay for Determination of the Mannose-Binding Lectin Gene Variants and an Algorithm for Calculation of Haplogenotype Combinations

Mannose-binding lectin (MBL) deficiency caused by the variability in the MBL2 gene is responsible for the susceptibility to and severity of various infectious and autoimmune diseases. A combination of six single nucleotide polymorphisms (SNPs) has a major impact on MBL levels in circulation. The aim...

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Detalles Bibliográficos
Autores principales: Mrazkova, Jana, Sistek, Petr, Lochman, Jan, Izakovicova Holla, Lydie, Danek, Zdenek, Borilova Linhartova, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918147/
https://www.ncbi.nlm.nih.gov/pubmed/33668563
http://dx.doi.org/10.3390/diagnostics11020301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918147/
https://www.ncbi.nlm.nih.gov/pubmed/33668563
http://dx.doi.org/10.3390/diagnostics11020301

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