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Nanopore Sequencing Resolves Elusive Long Tandem-Repeat Regions in Mitochondrial Genomes

Long non-coding, tandem-repetitive regions in mitochondrial (mt) genomes of many metazoans have been notoriously difficult to characterise accurately using conventional sequencing methods. Here, we show how the use of a third-generation (long-read) sequencing and informatic approach can overcome thi...

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Detalles Bibliográficos
Autores principales: Kinkar, Liina, Gasser, Robin B., Webster, Bonnie L., Rollinson, David, Littlewood, D. Timothy J., Chang, Bill C.H., Stroehlein, Andreas J., Korhonen, Pasi K., Young, Neil D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918261/
https://www.ncbi.nlm.nih.gov/pubmed/33670420
http://dx.doi.org/10.3390/ijms22041811