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Cellular hnRNPAB binding to viral nucleoprotein inhibits flu virus replication by blocking nuclear export of viral mRNA

Heterogeneous nuclear ribonucleoproteins (hnRNPs) play critical roles in the nuclear export, splicing, and sensing of RNA. However, the role of heterogeneous nuclear ribonucleoprotein A/B (hnRNPAB) is poorly understood. In this study, we report that hnRNPAB cooperates with nucleoprotein (NP) to rest...

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Detalles Bibliográficos
Autores principales: Wang, Xingbo, Lin, Lulu, Zhong, Yiye, Feng, Mingfang, Yu, Tianqi, Yan, Yan, Zhou, Jiyong, Liao, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918295/
https://www.ncbi.nlm.nih.gov/pubmed/33681726
http://dx.doi.org/10.1016/j.isci.2021.102160