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On the Protein Fibrillation Pathway: Oligomer Intermediates Detection Using ATR-FTIR Spectroscopy

Oligomeric intermediates on the pathway of amyloid fibrillation are suspected as the main cytotoxins responsible for amyloid-related pathogenicity. As they appear to be a part of the lag phase of amyloid fibrillation when analyzed using standard methods such as Thioflavin T (ThT) fluorescence, a mor...

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Detalles Bibliográficos
Autores principales: Milošević, Jelica, Prodanović, Radivoje, Polović, Natalija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918411/
https://www.ncbi.nlm.nih.gov/pubmed/33673072
http://dx.doi.org/10.3390/molecules26040970