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Valency and Binding Affinity Variations Can Regulate the Multilayered Organization of Protein Condensates with Many Components

Biomolecular condensates, which assemble via the process of liquid–liquid phase separation (LLPS), are multicomponent compartments found ubiquitously inside cells. Experiments and simulations have shown that biomolecular condensates with many components can exhibit multilayered organizations. Using...

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Detalles Bibliográficos
Autores principales: Sanchez-Burgos, Ignacio, Espinosa, Jorge R., Joseph, Jerelle A., Collepardo-Guevara, Rosana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918469/
https://www.ncbi.nlm.nih.gov/pubmed/33672806
http://dx.doi.org/10.3390/biom11020278