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Scrutinizing Mechanisms of the ‘Obesity Paradox in Sepsis’: Obesity Is Accompanied by Diminished Formation of Neutrophil Extracellular Traps (NETs) Due to Restricted Neutrophil–Platelet Interactions

Systemic inflammation is a detrimental condition associated with high mortality. However, obese individuals seem to have higher chances of surviving sepsis. To elucidate what immunological differences exist between obese and lean individuals we studied the course of endotoxemia in mice fed high-fat...

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Detalles Bibliográficos
Autores principales: Cichon, Iwona, Ortmann, Weronika, Santocki, Michal, Opydo-Chanek, Malgorzata, Kolaczkowska, Elzbieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918512/
https://www.ncbi.nlm.nih.gov/pubmed/33673387
http://dx.doi.org/10.3390/cells10020384