Cargando…
Scrutinizing Mechanisms of the ‘Obesity Paradox in Sepsis’: Obesity Is Accompanied by Diminished Formation of Neutrophil Extracellular Traps (NETs) Due to Restricted Neutrophil–Platelet Interactions
Systemic inflammation is a detrimental condition associated with high mortality. However, obese individuals seem to have higher chances of surviving sepsis. To elucidate what immunological differences exist between obese and lean individuals we studied the course of endotoxemia in mice fed high-fat...
Autores principales: | Cichon, Iwona, Ortmann, Weronika, Santocki, Michal, Opydo-Chanek, Malgorzata, Kolaczkowska, Elzbieta |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918512/ https://www.ncbi.nlm.nih.gov/pubmed/33673387 http://dx.doi.org/10.3390/cells10020384 |
Ejemplares similares
-
Metabolic Pathways Involved in Formation of Spontaneous and Lipopolysaccharide-Induced Neutrophil Extracellular Traps (NETs) Differ in Obesity and Systemic Inflammation
por: Cichon, Iwona, et al.
Publicado: (2021) -
Reduced Neutrophil Extracellular Trap (NET) Formation During Systemic Inflammation in Mice With Menkes Disease and Wilson Disease: Copper Requirement for NET Release
por: Cichon, Iwona, et al.
Publicado: (2020) -
On Neutrophil Extracellular Trap (NET) Removal: What We Know Thus Far and Why So Little
por: Santocki, Michal, et al.
Publicado: (2020) -
Age is the work of art? Impact of neutrophil and organism age on neutrophil extracellular trap formation
por: Ortmann, Weronika, et al.
Publicado: (2017) -
Itaconate Suppresses Formation of Neutrophil Extracellular Traps (NETs): Involvement of Hypoxia-Inducible Factor 1α (Hif-1α) and Heme Oxygenase (HO-1)
por: Burczyk, Gabriela, et al.
Publicado: (2022)