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Cytoplasmic cleavage of IMPA1 3′ UTR is necessary for maintaining axon integrity

The 3′ untranslated regions (3′ UTRs) of messenger RNAs (mRNAs) are non-coding sequences involved in many aspects of mRNA metabolism, including intracellular localization and translation. Incorrect processing and delivery of mRNA cause severe developmental defects and have been implicated in many ne...

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Detalles Bibliográficos
Autores principales: Andreassi, Catia, Luisier, Raphaëlle, Crerar, Hamish, Darsinou, Marousa, Blokzijl-Franke, Sasja, Lenn, Tchern, Luscombe, Nicholas M., Cuda, Giovanni, Gaspari, Marco, Saiardi, Adolfo, Riccio, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918530/
https://www.ncbi.nlm.nih.gov/pubmed/33626357
http://dx.doi.org/10.1016/j.celrep.2021.108778