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Cytoplasmic cleavage of IMPA1 3′ UTR is necessary for maintaining axon integrity
The 3′ untranslated regions (3′ UTRs) of messenger RNAs (mRNAs) are non-coding sequences involved in many aspects of mRNA metabolism, including intracellular localization and translation. Incorrect processing and delivery of mRNA cause severe developmental defects and have been implicated in many ne...
Autores principales: | Andreassi, Catia, Luisier, Raphaëlle, Crerar, Hamish, Darsinou, Marousa, Blokzijl-Franke, Sasja, Lenn, Tchern, Luscombe, Nicholas M., Cuda, Giovanni, Gaspari, Marco, Saiardi, Adolfo, Riccio, Antonella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918530/ https://www.ncbi.nlm.nih.gov/pubmed/33626357 http://dx.doi.org/10.1016/j.celrep.2021.108778 |
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