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Clinical Candidates Targeting the ATR–CHK1–WEE1 Axis in Cancer

SIMPLE SUMMARY: Selective killing of cancer cells is privileged mainstream in cancer treatment and targeted therapy represents the new tool with a potential to pursue this aim. It can also aid to overcome resistance of conventional chemo- or radio-therapy. Common mutations of cancer cells (defective...

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Detalles Bibliográficos
Autores principales: Gorecki, Lukas, Andrs, Martin, Korabecny, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918546/
https://www.ncbi.nlm.nih.gov/pubmed/33672884
http://dx.doi.org/10.3390/cancers13040795