The Cholesterol-Lowering Effect of Capsella Bursa-Pastoris Is Mediated via SREBP2 and HNF-1α-Regulated PCSK9 Inhibition in Obese Mice and HepG2 Cells

The objective of the present study was to investigate the mechanism by which capsella bursa-pastoris ethanol extract (CBE), containing 17.5 milligrams of icaritin per kilogram of the extract, and icaritin, mediate hypocholesterolemic activity via the low-density lipoprotein receptor (LDLR) and pro-p...

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Detalles Bibliográficos
Autores principales: Hwang, Jin-Taek, Choi, Eunji, Choi, Hyo-Kyoung, Park, Jae-Ho, Chung, Min-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918551/
https://www.ncbi.nlm.nih.gov/pubmed/33673187
http://dx.doi.org/10.3390/foods10020408