Analysis of Stop Codons within Prokaryotic Protein-Coding Genes Suggests Frequent Readthrough Events

Nonsense mutations turn a coding (sense) codon into an in-frame stop codon that is assumed to result in a truncated protein product. Thus, nonsense substitutions are the hallmark of pseudogenes and are used to identify them. Here we show that in-frame stop codons within bacterial protein-coding gene...

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Detalles Bibliográficos
Autores principales: Belinky, Frida, Ganguly, Ishan, Poliakov, Eugenia, Yurchenko, Vyacheslav, Rogozin, Igor B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918605/
https://www.ncbi.nlm.nih.gov/pubmed/33672790
http://dx.doi.org/10.3390/ijms22041876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918605/
https://www.ncbi.nlm.nih.gov/pubmed/33672790
http://dx.doi.org/10.3390/ijms22041876

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