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ZNF416 is a pivotal transcriptional regulator of fibroblast mechanoactivation

Matrix stiffness is a central regulator of fibroblast function. However, the transcriptional mechanisms linking matrix stiffness to changes in fibroblast phenotype are incompletely understood. Here, we evaluated the effect of matrix stiffness on genome-wide chromatin accessibility in freshly isolate...

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Detalles Bibliográficos
Autores principales: Jones, Dakota L., Meridew, Jeffrey A., Link, Patrick A., Ducharme, Merrick T., Lydon, Katherine L., Choi, Kyoung M., Caporarello, Nunzia, Tan, Qi, Diaz Espinosa, Ana Maria, Xiong, Yuning, Lee, Jeong-Heon, Ye, Zhenqing, Yan, Huihuang, Ordog, Tamas, Ligresti, Giovanni, Varelas, Xaralabos, Tschumperlin, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918622/
https://www.ncbi.nlm.nih.gov/pubmed/33625469
http://dx.doi.org/10.1083/jcb.202007152