Zoledronic Acid-Loaded β-TCP Inhibits Tumor Proliferation and Osteoclast Activation: Development of a Functional Bone Substitute for an Efficient Osteosarcoma Treatment

Osteosarcoma has a poor survival rate due to relapse and metastasis. Zoledronic acid (ZOL), an anti-resorptive and anti-tumor agent, is used for treating osteosarcoma. Delivery of ZOL to the target region is difficult due to its high binding affinity to bone minerals. This study developed a novel tr...

Descripción completa

Detalles Bibliográficos
Autores principales: Kameda, Yuka, Aizawa, Mamoru, Sato, Taira, Honda, Michiyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918630/
https://www.ncbi.nlm.nih.gov/pubmed/33672879
http://dx.doi.org/10.3390/ijms22041889

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918630/
https://www.ncbi.nlm.nih.gov/pubmed/33672879
http://dx.doi.org/10.3390/ijms22041889

Ejemplares similares