Copper‐Catalyzed Addition of Grignard Reagents to in situ Generated Indole‐Derived Vinylogous Imines

Chiral indole derivatives are ubiquitous motifs in pharmaceuticals and alkaloids. Herein, the first protocol for catalytic asymmetric conjugate addition of Grignard reagents to various sulfonyl indoles, offering a straightforward approach for the synthesis of chiral 3‐sec‐alkyl‐substituted indoles i...

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Detalles Bibliográficos
Autores principales: Ge, Luo, Zurro, Mercedes, Harutyunyan, Syuzanna R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918645/
https://www.ncbi.nlm.nih.gov/pubmed/32960461
http://dx.doi.org/10.1002/chem.202004232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918645/
https://www.ncbi.nlm.nih.gov/pubmed/32960461
http://dx.doi.org/10.1002/chem.202004232

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