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Drugs, Metabolites, and Lung Accumulating Small Lysosomotropic Molecules: Multiple Targeting Impedes SARS-CoV-2 Infection and Progress to COVID-19

Lysosomotropism is a biological characteristic of small molecules, independently present of their intrinsic pharmacological effects. Lysosomotropic compounds, in general, affect various targets, such as lipid second messengers originating from lysosomal enzymes promoting endothelial stress response...

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Detalles Bibliográficos
Autores principales: Blaess, Markus, Kaiser, Lars, Sommerfeld, Oliver, Csuk, René, Deigner, Hans-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918659/
https://www.ncbi.nlm.nih.gov/pubmed/33670304
http://dx.doi.org/10.3390/ijms22041797