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In Vitro Suppression of T Cell Proliferation Is a Conserved Function of Primary and Immortalized Human Cancer-Associated Fibroblasts

T cell immunotherapy is now a mainstay therapy for several blood-borne cancers as well as metastatic melanoma. Unfortunately, many epithelial tumors respond poorly to immunotherapy, and the reasons for this are not well understood. Cancer-associated fibroblasts (CAFs) are the most frequent non-neopl...

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Detalles Bibliográficos
Autores principales: Abuwarwar, Mohammed H., Baker, Alfie T., Harding, Jeffrey, Payne, Natalie L., Nagy, Andras, Knoblich, Konstantin, Fletcher, Anne L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918788/
https://www.ncbi.nlm.nih.gov/pubmed/33673197
http://dx.doi.org/10.3390/ijms22041827