Novel Potent and Selective DPP-4 Inhibitors: Design, Synthesis and Molecular Docking Study of Dihydropyrimidine Phthalimide Hybrids

Background: Dipeptidyl peptidase-4 (DPP-4) inhibitors have emerged as anti-hyperglycemic agents that improve glycemic control in type 2 diabetic patients, either as monotherapy or in combination with other antidiabetic drugs. Methods: A novel series of dihydropyrimidine phthalimide hybrids was synth...

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Detalles Bibliográficos
Autores principales: Mourad, Ahmed A. E., Khodir, Ahmed E., Saber, Sameh, Mourad, Mai A. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918823/
https://www.ncbi.nlm.nih.gov/pubmed/33670273
http://dx.doi.org/10.3390/ph14020144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918823/
https://www.ncbi.nlm.nih.gov/pubmed/33670273
http://dx.doi.org/10.3390/ph14020144

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