In Situ Crosslinked Hydrogel Depot for Sustained Antibody Release Improves Immune Checkpoint Blockade Cancer Immunotherapy

The therapeutic inhibition of immune checkpoints, including cytotoxic T lymphocyte-associated protein (CTLA)-4 and programmed cell death 1 (PD-1), through the use of function blocking antibodies can confer improved clinical outcomes by invigorating CD8(+) T cell-mediated anticancer immunity. However...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Jihoon, Francis, David M., Thomas, Susan N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918828/
https://www.ncbi.nlm.nih.gov/pubmed/33673289
http://dx.doi.org/10.3390/nano11020471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918828/
https://www.ncbi.nlm.nih.gov/pubmed/33673289
http://dx.doi.org/10.3390/nano11020471

Ejemplares similares