Pancreatic Tumorigenesis: Oncogenic KRAS and the Vulnerability of the Pancreas to Obesity

SIMPLE SUMMARY: Pancreatic cancer is a devastating disease with a poor survival rate, and oncogenic mutant KRAS is a major driver of its initiation and progression; however, effective strategies/drugs targeting major forms of mutant KRAS have not been forthcoming. Of note, obesity is known to worsen...

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Detalles Bibliográficos
Autores principales: Luo, Yongde, Li, Xiaokun, Ma, Jianjia, Abbruzzese, James L., Lu, Weiqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918840/
https://www.ncbi.nlm.nih.gov/pubmed/33668583
http://dx.doi.org/10.3390/cancers13040778

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918840/
https://www.ncbi.nlm.nih.gov/pubmed/33668583
http://dx.doi.org/10.3390/cancers13040778

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