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Unexpected Pro-Fibrotic Effect of MIF in Non-Alcoholic Steatohepatitis Is Linked to a Shift in NKT Cell Populations

Macrophage migration inhibitory factor (MIF) is a pleiotropic inflammatory cytokine with anti-fibrotic properties in toxic liver injury models and anti-steatotic functions in non-alcoholic fatty liver disease (NAFLD) attributed to the CD74/AMPK signaling pathway. As NAFLD progression is associated w...

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Detalles Bibliográficos
Autores principales: Heinrichs, Daniel, Brandt, Elisa F., Fischer, Petra, Köhncke, Janine, Wirtz, Theresa H., Guldiken, Nurdan, Djudjaj, Sonja, Boor, Peter, Kroy, Daniela, Weiskirchen, Ralf, Bucala, Richard, Wasmuth, Hermann E., Strnad, Pavel, Trautwein, Christian, Bernhagen, Jürgen, Berres, Marie-Luise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918903/
https://www.ncbi.nlm.nih.gov/pubmed/33525493
http://dx.doi.org/10.3390/cells10020252