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Unexpected Pro-Fibrotic Effect of MIF in Non-Alcoholic Steatohepatitis Is Linked to a Shift in NKT Cell Populations
Macrophage migration inhibitory factor (MIF) is a pleiotropic inflammatory cytokine with anti-fibrotic properties in toxic liver injury models and anti-steatotic functions in non-alcoholic fatty liver disease (NAFLD) attributed to the CD74/AMPK signaling pathway. As NAFLD progression is associated w...
Autores principales: | Heinrichs, Daniel, Brandt, Elisa F., Fischer, Petra, Köhncke, Janine, Wirtz, Theresa H., Guldiken, Nurdan, Djudjaj, Sonja, Boor, Peter, Kroy, Daniela, Weiskirchen, Ralf, Bucala, Richard, Wasmuth, Hermann E., Strnad, Pavel, Trautwein, Christian, Bernhagen, Jürgen, Berres, Marie-Luise |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918903/ https://www.ncbi.nlm.nih.gov/pubmed/33525493 http://dx.doi.org/10.3390/cells10020252 |
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