Cargando…

Ubiquitin Ligase SMURF2 Interacts with Filovirus VP40 and Promotes Egress of VP40 VLPs

Filoviruses Ebola (EBOV) and Marburg (MARV) are devastating high-priority pathogens capable of causing explosive outbreaks with high human mortality rates. The matrix proteins of EBOV and MARV, as well as eVP40 and mVP40, respectively, are the key viral proteins that drive virus assembly and egress...

Descripción completa

Detalles Bibliográficos
Autores principales: Shepley-McTaggart, Ariel, Schwoerer, Michael Patrick, Sagum, Cari A., Bedford, Mark T., Jaladanki, Chaitanya K., Fan, Hao, Cassel, Joel, Harty, Ronald N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918931/
https://www.ncbi.nlm.nih.gov/pubmed/33673144
http://dx.doi.org/10.3390/v13020288