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Role of Telomeres Shortening in Atherogenesis: An Overview

It is known that the shortening of the telomeres leads to cell senescence, accompanied by acquiring of pro-inflammatory phenotype. The expression of telomerase can elongate telomeres and resist the onset of senescence. The initiation of atherosclerosis is believed to be associated with local senesce...

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Detalles Bibliográficos
Autores principales: Yegorov, Yegor E., Poznyak, Anastasia V., Nikiforov, Nikita G., Starodubova, Antonina V., Orekhov, Alexander N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7918954/
https://www.ncbi.nlm.nih.gov/pubmed/33671887
http://dx.doi.org/10.3390/cells10020395