PF-3845, a Fatty Acid Amide Hydrolase Inhibitor, Directly Suppresses Osteoclastogenesis through ERK and NF-κB Pathways In Vitro and Alveolar Bone Loss In Vivo

Alveolar bone loss, the major feature of periodontitis, results from the activation of osteoclasts, which can consequently cause teeth to become loose and fall out; the development of drugs capable of suppressing excessive osteoclast differentiation and function is beneficial for periodontal disease...

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Detalles Bibliográficos
Autores principales: Ihn, Hye-Jung, Kim, Yi-Seul, Lim, Soomin, Bae, Jong-Sup, Jung, Jae-Chang, Kim, Yeo-Hyang, Park, Jin-Woo, Wang, Zhao, Koh, Jeong-Tae, Bae, Yong-Chul, Baek, Moon-Chang, Park, Eui-Kyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919013/
https://www.ncbi.nlm.nih.gov/pubmed/33671948
http://dx.doi.org/10.3390/ijms22041915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919013/
https://www.ncbi.nlm.nih.gov/pubmed/33671948
http://dx.doi.org/10.3390/ijms22041915

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