Preparation and Bioevaluation of Novel (99m)Tc-Labeled Complexes with a 2-Nitroimidazole HYNIC Derivative for Imaging Tumor Hypoxia

To develop novel (99m)Tc-labeled single-photon emission computed tomography (SPECT) radiotracers for imaging hypoxia, a novel HYNICNM ligand (6-hydrazinonicotinamide (HYNIC) 2-nitroimidazole derivative) was designed and synthesized. It was radiolabeled with technetium-99m using tricine/trisodium tri...

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Detalles Bibliográficos
Autores principales: Ruan, Qing, Gan, Qianqian, Zhang, Xuran, Fang, Si’an, Zhang, Junbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919024/
https://www.ncbi.nlm.nih.gov/pubmed/33671923
http://dx.doi.org/10.3390/ph14020158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919024/
https://www.ncbi.nlm.nih.gov/pubmed/33671923
http://dx.doi.org/10.3390/ph14020158

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