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CircWAC induces chemotherapeutic resistance in triple-negative breast cancer by targeting miR-142, upregulating WWP1 and activating the PI3K/AKT pathway

BACKGROUND: Chemotherapeutic resistance is the main cause of clinical treatment failure and poor prognosis in triple-negative breast cancer (TNBC). There is no research on chemotherapeutic resistance in TNBC from the perspective of circular RNAs (circRNAs). METHODS: TNBC-related circRNAs were identi...

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Detalles Bibliográficos
Autores principales: Wang, Lei, Zhou, Yehui, Jiang, Liang, Lu, Linlin, Dai, Tiantian, Li, Aoshuang, Chen, Yan, Zhang, Lifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919093/
https://www.ncbi.nlm.nih.gov/pubmed/33648498
http://dx.doi.org/10.1186/s12943-021-01332-8