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CircWAC induces chemotherapeutic resistance in triple-negative breast cancer by targeting miR-142, upregulating WWP1 and activating the PI3K/AKT pathway
BACKGROUND: Chemotherapeutic resistance is the main cause of clinical treatment failure and poor prognosis in triple-negative breast cancer (TNBC). There is no research on chemotherapeutic resistance in TNBC from the perspective of circular RNAs (circRNAs). METHODS: TNBC-related circRNAs were identi...
Autores principales: | Wang, Lei, Zhou, Yehui, Jiang, Liang, Lu, Linlin, Dai, Tiantian, Li, Aoshuang, Chen, Yan, Zhang, Lifeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919093/ https://www.ncbi.nlm.nih.gov/pubmed/33648498 http://dx.doi.org/10.1186/s12943-021-01332-8 |
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