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Two polymorphic mutations in promoter region of DNA polymerase β in relatively higher percentage of thymic hyperplasia patients

BACKGROUND: DNA polymerase β is one of the key enzymes involved in the repair of DNA damage, and its high or low expression is closely related to tumorigenesis. In a previous study on lung cancer, we found three genetic mutations in the promoter region of the Polb gene could be detected in the Han C...

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Detalles Bibliográficos
Autores principales: Wu, Qingjun, Zhou, Shan, Liu, Jian, Tong, Hongfeng, Sun, Yaoguang, Tian, Wenxin, Yu, Hanbo, Huang, Chuan, Li, Donghang, Jiao, Peng, Ma, Chao, Cai, Jianping, Dai, Dapeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919162/
https://www.ncbi.nlm.nih.gov/pubmed/33314687
http://dx.doi.org/10.1111/1759-7714.13773