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Population Pharmacokinetics of Phosphocreatine and Its Metabolite Creatine in Children With Myocarditis

Objective: This study aimed to develop a parent-metabolite joint population pharmacokinetic model to characterize the pharmacokinetic (PK) profile for phosphocreatine (PCr) and its metabolite creatine (Cr) in children with myocarditis and to use this model to study the PK profile of different dosing...

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Detalles Bibliográficos
Autores principales: He, Huan, Zhang, Meng, Zhao, Li-bo, Sun, Ning, Zhang, Yi, Yuan, Yue, Wang, Xiao-ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919190/
https://www.ncbi.nlm.nih.gov/pubmed/33658923
http://dx.doi.org/10.3389/fphar.2020.574141