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Risk of Bleeding Associated With Ibrutinib in Patients With B-Cell Malignancies: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Background: Ibrutinib is an oral covalent Bruton’s tyrosine kinase inhibitor that has been approved for chronic lymphocytic leukemia (CLL)/small lymphocytic leukemia and some other B-cell malignancies. Some studies have found an increased risk of bleeding with ibrutinib. Some studies, however, found...

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Detalles Bibliográficos
Autores principales: Wang, Jinjin, Zhao, Ailin, Zhou, Hui, Zhu, Jinbing, Niu, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919192/
https://www.ncbi.nlm.nih.gov/pubmed/33658926
http://dx.doi.org/10.3389/fphar.2020.580622