A Targeted and Tuneable DNA Damage Tool Using CRISPR/Cas9

Mammalian cells are constantly subjected to a variety of DNA damaging events that lead to the activation of DNA repair pathways. Understanding the molecular mechanisms of the DNA damage response allows the development of therapeutics which target elements of these pathways. Double-strand breaks (DSB...

Descripción completa

Detalles Bibliográficos
Autores principales: Emmanouilidis, Ioannis, Fili, Natalia, Cook, Alexander W., Hari-Gupta, Yukti, dos Santos, Ália, Wang, Lin, Martin-Fernandez, Marisa L., Ellis, Peter J. I., Toseland, Christopher P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919286/
https://www.ncbi.nlm.nih.gov/pubmed/33672015
http://dx.doi.org/10.3390/biom11020288

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919286/
https://www.ncbi.nlm.nih.gov/pubmed/33672015
http://dx.doi.org/10.3390/biom11020288

Ejemplares similares