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TMEM52B suppression promotes cancer cell survival and invasion through modulating E-cadherin stability and EGFR activity

BACKGROUND: TMEM52B is a novel gene broadly expressed in a variety of normal human tissues. However, the biological function of TMEM52B expression in cancer is largely unknown. METHODS: The effects of TMEM52B on tumor growth and metastasis were investigated in vitro and in vivo, and the underlying b...

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Detalles Bibliográficos
Autores principales: Lee, Yunhee, Ko, Dongjoon, Yoon, Junghwa, Lee, Younghoon, Kim, Semi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919321/
https://www.ncbi.nlm.nih.gov/pubmed/33641663
http://dx.doi.org/10.1186/s13046-021-01828-7