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TMEM52B suppression promotes cancer cell survival and invasion through modulating E-cadherin stability and EGFR activity
BACKGROUND: TMEM52B is a novel gene broadly expressed in a variety of normal human tissues. However, the biological function of TMEM52B expression in cancer is largely unknown. METHODS: The effects of TMEM52B on tumor growth and metastasis were investigated in vitro and in vivo, and the underlying b...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919321/ https://www.ncbi.nlm.nih.gov/pubmed/33641663 http://dx.doi.org/10.1186/s13046-021-01828-7 |