Cytotoxicity Evaluation of Chloroquine and Hydroxychloroquine in Multiple Cell Lines and Tissues by Dynamic Imaging System and Physiologically Based Pharmacokinetic Model

Chloroquine (CQ) and hydroxychloroquine (HCQ) have been challenged in treating COVID-19 patients and still under debate due to the uncertainty regarding the effectiveness and safety, and there is still lack of the systematic study on the toxicity of these two drugs. To further uncover the toxicity p...

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Detalles Bibliográficos
Autores principales: Yang, Jianling, Guo, Zhengyang, Liu, Xu, Liu, Qi, Wu, Meng, Yao, Xueting, Liu, Yang, Cui, Cheng, Li, Haiyan, Song, Chunli, Liu, Dongyang, Xue, Lixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919379/
https://www.ncbi.nlm.nih.gov/pubmed/33658924
http://dx.doi.org/10.3389/fphar.2020.574720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919379/
https://www.ncbi.nlm.nih.gov/pubmed/33658924
http://dx.doi.org/10.3389/fphar.2020.574720

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