Structure and comparison of the motor domain of centromere-associated protein E

Centromere-associated protein E (CENP-E) plays an essential role in mitosis and is a target candidate for anticancer drugs. However, it is difficult to design small-molecule inhibitors of CENP-E kinesin motor ATPase activity owing to a lack of structural information on the CENP-E motor domain in com...

Descripción completa

Detalles Bibliográficos
Autores principales: Shibuya, Asuka, Ogo, Naohisa, Sawada, Jun-ichi, Asai, Akira, Yokoyama, Hideshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2021
Materias:
Isdsb2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919405/
https://www.ncbi.nlm.nih.gov/pubmed/33645531
http://dx.doi.org/10.1107/S2059798321000176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919405/
https://www.ncbi.nlm.nih.gov/pubmed/33645531
http://dx.doi.org/10.1107/S2059798321000176

Ejemplares similares