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Circadian hepatocyte clocks keep synchrony in the absence of a master pacemaker in the suprachiasmatic nucleus or other extrahepatic clocks

It has been assumed that the suprachiasmatic nucleus (SCN) synchronizes peripheral circadian oscillators. However, this has never been convincingly shown, since biochemical time series experiments are not feasible in behaviorally arrhythmic animals. By using long-term bioluminescence recording in fr...

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Detalles Bibliográficos
Autores principales: Sinturel, Flore, Gos, Pascal, Petrenko, Volodymyr, Hagedorn, Claudia, Kreppel, Florian, Storch, Kai-Florian, Knutti, Darko, Liani, Andre, Weitz, Charles, Emmenegger, Yann, Franken, Paul, Bonacina, Luigi, Dibner, Charna, Schibler, Ueli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919413/
https://www.ncbi.nlm.nih.gov/pubmed/33602874
http://dx.doi.org/10.1101/gad.346460.120