A coregulator shift, rather than the canonical switch, underlies thyroid hormone action in the liver

Thyroid hormones (THs) are powerful regulators of metabolism with major effects on body weight, cholesterol, and liver fat that have been exploited pharmacologically for many years. Activation of gene expression by TH action is canonically ascribed to a hormone-dependent “switch” from corepressor to...

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Detalles Bibliográficos
Autores principales: Shabtai, Yehuda, Nagaraj, Nagaswaroop K., Batmanov, Kirill, Cho, Young-Wook, Guan, Yuxia, Jiang, Chunjie, Remsberg, Jarrett, Forrest, Douglas, Lazar, Mitchell A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919419/
https://www.ncbi.nlm.nih.gov/pubmed/33602873
http://dx.doi.org/10.1101/gad.345686.120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919419/
https://www.ncbi.nlm.nih.gov/pubmed/33602873
http://dx.doi.org/10.1101/gad.345686.120

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