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Systematic detection of brain protein-coding genes under positive selection during primate evolution and their roles in cognition

The human brain differs from that of other primates, but the genetic basis of these differences remains unclear. We investigated the evolutionary pressures acting on almost all human protein-coding genes (N = 11,667; 1:1 orthologs in primates) based on their divergence from those of early hominins,...

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Detalles Bibliográficos
Autores principales: Dumas, Guillaume, Malesys, Simon, Bourgeron, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7919455/
https://www.ncbi.nlm.nih.gov/pubmed/33441416
http://dx.doi.org/10.1101/gr.262113.120